The Role of Garlic in Metabolic Diseases: A Review

J Med Food. 2022 Jul;25(7):683-694. doi: 10.1089/jmf.2021.0146. Epub 2022 Jun 8.

Abstract

Garlic (Allium sativum L.) is a popular spice that has been widely used for thousands of years in traditional medicine. Several organosulfur compounds in garlic have been linked to its beneficial effects on health. Evidence from preclinical studies and clinical trials supports garlic's antihypertensive, antidiabetic, antiobesity, and hypolipidemic effects. This study aims to summarize clinical trial evidence regarding the effects of garlic on metabolic diseases and its mechanisms of action.

Keywords: dyslipidemia; garlic; hypertension; metabolic syndrome; obesity; type 2 diabetes mellitus.

Publication types

  • Review

MeSH terms

  • Antioxidants / therapeutic use
  • Biological Products*
  • Garlic*
  • Humans
  • Hypoglycemic Agents
  • Metabolic Diseases* / drug therapy
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use

Substances

  • Antioxidants
  • Biological Products
  • Hypoglycemic Agents
  • Plant Extracts