The bed nucleus of the stria terminalis in the rat: regional sex differences controlled by gonadal steroids early after birth

Brain Res. 1987 Apr;429(2):295-300. doi: 10.1016/0165-3806(87)90110-6.


The effects of postnatal (on day 1 (D1) after birth) male orchidectomy and female androgenization on the bed nucleus of the stria terminalis (BNST) were studied. The volume of the medial posterior region of the BNST was greater in the control males than in the control females. Postnatal treatment reversed these differences. Sex differences were also found in the medial anterior region of the BNST where female rats always showed a greater volume than did the males. Female androgenization on D1 did not affect the volume of the BNST medial anterior region. However, D1 male orchidectomy did increase significantly the volume of this region. No sex differences were found in lateral, ventral or intermediate BNST divisions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Androgens / physiology*
  • Animals
  • Female
  • Limbic System / growth & development*
  • Male
  • Orchiectomy
  • Rats
  • Rats, Inbred Strains
  • Sex Characteristics*
  • Testosterone / pharmacology


  • Androgens
  • Testosterone