Case Report: Baló's Concentric Sclerosis-Like Lesion in a Patient With Relapsing-Remitting Multiple Sclerosis Treated With Dimethyl Fumarate

Karolina Kania; Wojciech Ambrosius; Wojciech Kozubski; Alicja Kalinowska

doi:10.3389/fneur.2022.891113

Case Report: Baló's Concentric Sclerosis-Like Lesion in a Patient With Relapsing-Remitting Multiple Sclerosis Treated With Dimethyl Fumarate

Front Neurol. 2022 May 23:13:891113. doi: 10.3389/fneur.2022.891113. eCollection 2022.

Authors

Karolina Kania¹, Wojciech Ambrosius¹, Wojciech Kozubski¹, Alicja Kalinowska²

Affiliations

¹ Department of Neurology, Poznan University of Medical Sciences, Poznan, Poland.
² Division of Neurochemistry and Neuropathology, Department of Neurology, Poznan University of Medical Sciences, Poznan, Poland.

Abstract

Baló's concentric sclerosis (BCS) is a rare demyelinating disorder characterized by acute or subacute neurological symptoms associated with characteristic lesions of concentric onion skin appearance on MRI images and in pathology. The connection between BCS and classic MS is still a subject of debates. Our report presents a case of a patient who developed a symptomatic Baló-like lesion following several years of classical relapsing-remitting multiple sclerosis treated with dimethyl fumarate.

Keywords: Baló concentric sclerosis; Baló disease; MRI; dimethyl fumarate; multiple sclerosis.

Publication types

Case Reports