Intrahepatic cholestasis of pregnancy with marked elevation of transaminases in a black American

Dig Dis Sci. 1987 Jun;32(6):665-8. doi: 10.1007/BF01296169.


A case of intrahepatic cholestasis of pregnancy (ICP) in a black American is presented. This is the first case reported in a black. Marked elevation of transaminases with mild biochemical evidence of cholestasis was initially suggestive of viral hepatitis. A clinical course characterized by pruritus with minimal constitutional symptoms, rapid resolution of biochemical abnormalities after delivery, and negative hepatitis A and B serologies was consistent with the diagnosis of ICP. Review of the classic features of ICP with emphasis on some unusual aspects of the disorder is included.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Black People*
  • Black or African American
  • Cholestasis, Intrahepatic / diagnosis
  • Cholestasis, Intrahepatic / enzymology*
  • Cholestasis, Intrahepatic / genetics
  • Diagnosis, Differential
  • Female
  • Hepatitis / diagnosis
  • Humans
  • Pregnancy
  • Pregnancy Complications / diagnosis
  • Pregnancy Complications / enzymology*
  • Pregnancy Complications / genetics
  • Transaminases / blood*


  • Transaminases