Surgical management of locally advanced breast cancer: Recommendations of the Brazilian Society of Surgical Oncology

J Surg Oncol. 2022 Jul;126(1):57-67. doi: 10.1002/jso.26890.


The Brazilian Society of Surgical Oncology organized a group of oncological surgeons to discuss surgical aspects associated with locally advanced breast carcinoma. This article reviews the indications, different surgeries (thoracoabdominal or myocutaneous flaps), and associated complications. It discusses special conditions such as invasion of the chest wall and interscapular thoracic disarticulation. It makes recommendations based on the literature regarding clinical findings, tumor conditions, response to neoadjuvant therapy, choice of flaps in surgery, and tumor biology.

Keywords: breast neoplasm; locally advanced tumors; myocutaneous flaps; peroperative complication; surgical flaps.

Publication types

  • Review

MeSH terms

  • Brazil
  • Breast Neoplasms* / pathology
  • Breast Neoplasms* / surgery
  • Female
  • Humans
  • Neoplasm Recurrence, Local / surgery
  • Surgical Flaps
  • Surgical Oncology*
  • Thoracic Wall* / surgery