Vitamin B12 and brain development

Eur J Pediatr. 1987 Mar;146(2):201-5. doi: 10.1007/BF02343237.


This is a report of a 1 1/2-year-old male with megaloblastic anaemia and a progressive neurological disorder clinically resembling leucodystrophy. The child was exclusively breast fed and his mother had been a strict vegetarian for more than 4 years before the child was born. After Vitamin B12 therapy the anaemia disappeared and the neurological condition dramatically improved.

Publication types

  • Case Reports

MeSH terms

  • Anemia, Macrocytic / etiology*
  • Anemia, Megaloblastic / etiology*
  • Atrophy / etiology
  • Brain / pathology*
  • Breast Feeding*
  • Diet, Vegetarian / adverse effects*
  • Female
  • Humans
  • Infant
  • Male
  • Pregnancy
  • Vitamin B 12 Deficiency / complications*