A Report of a Case With Pediatric Ovarian Steroid Cell Tumor, Not Otherwise Specified, Found With Precocious Puberty

J Pediatr Hematol Oncol. 2023 May 1;45(4):e522-e524. doi: 10.1097/MPH.0000000000002496. Epub 2022 Jun 7.

Abstract

A 4-year-old girl was admitted to our hospital because of precocious puberty. Radiologic findings revealed a fist-sized solid tumor in the left ovary without ascites, peritoneal dissemination, and distant metastasis. The patient underwent left salpingo-oophorectomy without spillage. The size of the excised tumor was 10.0×9.0×4.8 cm. On pathologic examination, the tumor was diagnosed as an ovarian steroid cell tumor, not otherwise specified. In the present case, although the diameter of the tumor (>7 cm) and three mitoses per 10 high-power fields represented some potential for malignancy, we opted for careful observation without chemotherapy as the tumor was of clinical stage Ia.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Child, Preschool
  • Female
  • Humans
  • Ovarian Neoplasms* / complications
  • Ovarian Neoplasms* / diagnosis
  • Ovarian Neoplasms* / surgery
  • Puberty, Precocious* / etiology
  • Sex Cord-Gonadal Stromal Tumors*
  • Steroids

Substances

  • Steroids