Effectiveness and acceptability of intranasal povidone-iodine decolonization among fracture fixation surgery patients to reduce Staphylococcus aureus nasal colonization

Marin L Schweizer; Loreen A Herwaldt; Linda Boyken; Jean Pottinger; Rachel Quinn; Daniel J Diekema; Fiona Armstrong-Pavlik; Melissa Ward; Poorani Sekar; Michael C Willey

doi:10.1017/ice.2022.134

Effectiveness and acceptability of intranasal povidone-iodine decolonization among fracture fixation surgery patients to reduce Staphylococcus aureus nasal colonization

Infect Control Hosp Epidemiol. 2022 Jun 15;1-3. doi: 10.1017/ice.2022.134. Online ahead of print.

Authors

Affiliations

¹ Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa.
² Center for Access and Delivery Research and Evaluation, Iowa City VA Health Care System, Iowa City, Iowa.
³ Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, Iowa.
⁴ Department of Orthopedics and Rehabilitation, University of Iowa Hospitals & Clinics, Iowa City, Iowa.

PMID: 35701860
DOI: 10.1017/ice.2022.134

Abstract

We evaluated povidone-iodine (PVI) decolonization among 51 fracture-fixation surgery patients. PVI was applied twice on the day of surgery. Patients were tested for S. aureus nasal colonization and surveyed. Mean S. aureus concentrations decreased from 3.13 to 1.15 CFU/mL (P = .03). Also, 86% of patients stated that they felt neutral or positive about their PVI experience.