Disseminated Histiocytic Sarcoma in Two Free-Living Florida Manatees (Trichechus manatus latirostris)

J Wildl Dis. 2022 Jul 1;58(3):685-688. doi: 10.7589/JWD-D-21-00138.


During necropsy of two manatees, masses in multiple organs including liver and spleen were identified. They were composed of neoplastic round to spindle-shaped cells, positive for vimentin, Iba-1, lysozyme, and Mac387, consistent with histiocytic sarcoma. One manatee also had an undifferentiated sarcoma that may have arisen from the histiocytic sarcoma.

MeSH terms

  • Animals
  • Histiocytic Sarcoma* / veterinary
  • Trichechus
  • Trichechus manatus*