Modifying insulin to improve performance

Science. 2022 Jun 17;376(6599):1270-1271. doi: 10.1126/science.abq7217. Epub 2022 Jun 16.

Authors

Nai-Pin Lin¹, Danny Hung-Chieh Chou¹

Affiliation

¹ Stanford University, School of Medicine, Palo Alto, CA, USA.

PMID: 35709283
DOI: 10.1126/science.abq7217

Abstract

A platform to enable precise modifications of insulin could improve drug functionality.

Publication types

Comment

MeSH terms

Biocatalysis
Humans
Insulin* / analogs & derivatives
Insulin* / chemistry
Insulin* / therapeutic use
Penicillin Amidase* / chemistry
Penicillin Amidase* / genetics
Protein Engineering* / methods

Substances

Insulin
Penicillin Amidase