Objective: To observe the clinical efficacy of different treatment frequency of auricular bloodletting combined with auricular point sticking for acne vulgaris.
Methods: A total of 90 patients with acne vulgaris were randomized into a treatment group 1 (30 cases, 2 cases dropped off), a treatment group 2 (30 cases, 4 cases dropped off) and a treatment group 3 (30 cases, 5 cases dropped off). Combination therapy of auricular bloodletting and auricular point sticking at Fei (CO14), Shenmen (TF4), Neifenmi (CO18) and Shenshangxian (TG2p) were given once a week, twice a week and 3 times a week in the treatment group 1, the treatment group 2 and the treatment group 3 respectively, 4 weeks were as one course and totally 3 courses were required in the 3 groups. Before treatment and after 1, 2, 3 courses of treatment, the scores of global acne grading system (GAGS), skin lesion and quality of life-acne (QoL-Acne) were observed, the clinical efficacy was evaluated after 3 courses of treatment and the recurrence rate was evaluated in follow-up of 1 month after treatment in the 3 groups.
Results: Compared before treatment, the scores of GAGS and skin lesion were decreased at each time point in the 3 groups (P<0.05), the QoL-Acne scores were increased after 1 course of treatment in the treatment group 3 and after 2, 3 courses of treatment in the 3 groups (P<0.05). There were no statistical differences in scores of GAGS, skin lesion and QoL-Acne among the 3 groups (P>0.05). There were no statistical differences in effective rate and recurrence rate among the 3 groups (P>0.05).
Conclusion: Different frequency of auricular bloodletting combined with auricular point sticking have similar efficacy in treating acne vulgaris, all can improve the skin lesion and quality of life in patients with acne vulgaris, and have a cumulative effect and good long-term curative effect.
目的：观察耳穴刺络结合耳穴贴压不同治疗频次对寻常型痤疮临床疗效的影响。方法：将90例寻常型痤疮患者随机分为治疗1组（30例，脱落2例）、治疗2组（30例，脱落4例）和治疗3组（30例，脱落5例）。治疗1组、治疗2组及治疗3组分别接受每周1、2、3次耳尖刺络结合耳穴贴压（肺、神门、内分泌和肾上腺）治疗，每日1次，均治疗4周为一疗程，共3个疗程。分别于治疗前及治疗1、2、3个疗程后记录3组患者全球痤疮分级系统（GAGS）评分、皮损积分、痤疮特异性生活质量量表（QoL-Acne）评分；于治疗3个疗程后评定3组疗效，于治疗后1个月随访评定复发率。结果：与治疗前比较，3组患者治疗后各时间点GAGS评分、皮损积分均降低（P<0.05），治疗3组患者治疗1个疗程后及3组患者治疗2、3个疗程后QoL-Acne评分均升高（P<0.05）；3组GAGS评分、皮损积分及QoL-Acne评分组间比较，差异均无统计学意义（P>0.05）。3组有效率及复发率比较，差异均无统计学意义（P>0.05）。结论：不同频次耳穴刺络结合耳穴贴压疗效相当，均能改善寻常型痤疮皮损症状，提高患者生活质量，且均具有累积效应及良好的远期疗效。.
Keywords: acne vulgaris; auricular bloodletting; auricular point sticking; randomized controlled trial (RCT); treatment frequency.