Estimated incubation period for monkeypox cases confirmed in the Netherlands, May 2022

Euro Surveill. 2022 Jun;27(24):2200448. doi: 10.2807/1560-7917.ES.2022.27.24.2200448.


In May 2022, monkeypox outbreaks have been reported in countries not endemic for monkeypox. We estimated the monkeypox incubation period, using reported exposure and symptom-onset times for 18 cases detected and confirmed in the Netherlands up to 31 May 2022. Mean incubation period was 9.0 [corrected] days (5th-95th percentiles: 4.2-17.3), underpinning the current recommendation to monitor or isolate/quarantine case contacts for 21 days. However, as the incubation period may differ between different transmission routes, further epidemiological investigations are needed.

Keywords: Monkeypox; epidemiology; incubation period; modelling; poxvirus; quarantine; smallpox; statistics; symptom onset; varicella virus infection (chickenpox).

MeSH terms

  • Disease Outbreaks*
  • Humans
  • Infectious Disease Incubation Period
  • Monkeypox virus
  • Monkeypox* / diagnosis
  • Monkeypox* / epidemiology
  • Netherlands / epidemiology