This article presents features of uncommon high-grade endometrial carcinomas that often pose a significant diagnostic challenge. An update on undifferentiated and dedifferentiated endometrial carcinoma is first provided, followed by discussions on more recently defined entities such as mesonephric-like carcinoma of the endometrium and gastric-type endometrial carcinomas. Finally, endometrial carcinoma with germ cell or trophoblastic-like components is discussed.
Keywords: Dedifferentiated endometrial carcinoma; Endometrial carcinoma with germ cell or trophoblastic-like components; Gastric-type endometrial carcinoma; Mesonephric-like carcinoma of the endometrium; Undifferentiated endometrial carcinoma.
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