Cardiovascular Imaging in Cardio-Oncology: The Role of Echocardiography and Cardiac MRI in Modern Cardio-Oncology

John Alan Gambril; Aaron Chum; Akash Goyal; Patrick Ruz; Katarzyna Mikrut; Orlando Simonetti; Hardeep Dholiya; Brijesh Patel; Daniel Addison

doi:10.1016/j.hfc.2022.02.007

Cardiovascular Imaging in Cardio-Oncology: The Role of Echocardiography and Cardiac MRI in Modern Cardio-Oncology

Heart Fail Clin. 2022 Jul;18(3):455-478. doi: 10.1016/j.hfc.2022.02.007.

Authors

John Alan Gambril¹, Aaron Chum², Akash Goyal³, Patrick Ruz², Katarzyna Mikrut⁴, Orlando Simonetti⁵, Hardeep Dholiya⁶, Brijesh Patel⁷, Daniel Addison⁸

Affiliations

¹ Department of Internal Medicine, Ohio State University Wexner Medical Center, Columbus, OH, USA; Cardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA. Electronic address: https://twitter.com/GambrilAlan.
² Cardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA; Division of Cardiovascular Medicine, Davis Heart & Lung Research Institute, 473 West 12th Avenue, Suite 200, Columbus, OH 43210, USA.
³ Cardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA; Division of Cardiovascular Medicine, Davis Heart & Lung Research Institute, 473 West 12th Avenue, Suite 200, Columbus, OH 43210, USA. Electronic address: https://twitter.com/agoyalMD.
⁴ Cardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA. Electronic address: https://twitter.com/KatieMikrut.
⁵ Cardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA; Division of Cardiovascular Medicine, Davis Heart & Lung Research Institute, 473 West 12th Avenue, Suite 200, Columbus, OH 43210, USA; Department of Internal Medicine, The Ohio State University Medical Center, Columbus, OH, USA; Department of Radiology, The Ohio State University Medical Center, Columbus, OH, USA.
⁶ Cardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA; Division of Cardiovascular Medicine, Davis Heart & Lung Research Institute, 473 West 12th Avenue, Suite 200, Columbus, OH 43210, USA. Electronic address: https://twitter.com/Hardeep_10.
⁷ Division of Cardiovascular Medicine, Davis Heart & Lung Research Institute, 473 West 12th Avenue, Suite 200, Columbus, OH 43210, USA; Cardio-Oncology Program, Heart and Vascular Institute, West Virginia University, Morgantown, WV, USA.
⁸ Cardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center, Columbus, OH, USA; Division of Cancer Prevention and Control, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH, USA. Electronic address: daniel.addison@osumc.edu.

Abstract

Cardiovascular (CV) events are an increasingly common limitation of effective anticancer therapy. Over the last decade imaging has become essential to patients receiving contemporary cancer therapy. Herein we discuss the current state of CV imaging in cardio-oncology. We also provide a practical apparatus for the use of imaging in everyday cardiovascular care of oncology patients to improve outcomes for those at risk for cardiotoxicity, or with established cardiovascular disease. Finally, we consider future directions in the field given the wave of new anticancer therapies.

Keywords: Advanced imaging; Cardiac MRI; Cardio-oncology; Echocardiography; Immunotherapy toxicity.

Publication types

Review

MeSH terms

Antineoplastic Agents* / adverse effects
Cardiotoxicity / diagnostic imaging
Cardiotoxicity / etiology
Cardiovascular Diseases* / diagnostic imaging
Echocardiography
Humans
Magnetic Resonance Imaging
Medical Oncology
Neoplasms* / complications
Neoplasms* / diagnostic imaging
Neoplasms* / drug therapy

Substances

Antineoplastic Agents

Abstract

Publication types

MeSH terms

Substances

Grants and funding