Effects of contraction bias on the decision process in the macaque prefrontal cortex

Cereb Cortex. 2023 Mar 10;33(6):2958-2968. doi: 10.1093/cercor/bhac253.

Abstract

Our representation of magnitudes such as time, distance, and size is not always veridical because it is affected by multiple biases. From a Bayesian perspective, estimation errors are considered to be the result of an optimization mechanism for the behavior in a noisy environment by integrating previous experience with the incoming sensory information. One influence of the distribution of past stimuli on perceptual decisions is represented by the regression toward the mean, a type of contraction bias. Using a spatial discrimination task with 2 stimuli presented sequentially at different distances from the center, we show that this bias is also present in macaques when comparing the magnitude of 2 distances. We found that the contraction of the first stimulus magnitude toward the center of the distribution accounted for some of the changes in performance, even more so than the effect of difficulty related to the ratio between stimulus magnitudes. At the neural level in the dorsolateral prefrontal cortex, the coding of the decision after the presentation of the second stimulus reflected the effect of the contraction bias on the discriminability of the stimuli at the behavioral level.

Keywords: Bayesian inference; central tendency bias; contraction bias; decision; monkeys; prefrontal cortex; regression toward the mean; spatial discrimination.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bayes Theorem
  • Bias
  • Macaca mulatta
  • Prefrontal Cortex*
  • Reaction Time