Magnesium Citrate Toxicity: A Case Report of a Patient With Significantly Altered Gastrointestinal Anatomy

S D Med. 2022 May;75(5):202-205.

Abstract

Magnesium citrate is a widely used over the counter drug with little to no safety concerns. This case study describes the development of magnesium toxicity after a single dose of magnesium citrate in a patient with extensive prior gastrointestinal surgery for pancreatic adenocarcinoma. The surgery resulted in extensively altered gastrointestinal physiology and several mechanisms could have influenced the abnormal absorption of magnesium seen in this patient. The patient had normal renal function pointing to a different mechanism than previously reported magnesium toxicities.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma* / drug therapy
  • Adenocarcinoma* / surgery
  • Citrates
  • Citric Acid
  • Humans
  • Magnesium
  • Organometallic Compounds
  • Pancreatic Neoplasms* / drug therapy
  • Pancreatic Neoplasms* / surgery

Substances

  • Citrates
  • Organometallic Compounds
  • Citric Acid
  • Magnesium
  • magnesium citrate