Surgical management of Graves' disease: historical context and single institution experience

N Z Med J. 2022 Feb 4;135(1549):43-49.

Abstract

Aim: To describe indications and outcomes of total thyroidectomy for Graves' disease in a large New Zealand endocrine surgery unit, and to compare these results to international studies.

Methods: We analysed a prospectively collected database to describe the indications and outcomes of surgery for Graves' disease between December 2001 and January 2021.

Results: Among 64 patients who underwent total thyroidectomy at our tertiary centre for Graves' hyperthyroidism, Graves' ophthalmopathy and patient preference/aversion to radioactive iodine were the most common indications for surgery. Total thyroidectomy resulted in long-term control of thyrotoxicosis in all patients. There were no incidences of recurrent laryngeal nerve injury. One patient (1.6%) suffered permanent hypoparathyroidism.

Conclusion: Total thyroidectomy is a safe and effective treatment for Graves' disease. In our population, total thyroidectomy functions as a second-line treatment for Graves' disease.

MeSH terms

  • Graves Disease* / surgery
  • Graves Ophthalmopathy*
  • Humans
  • Iodine Radioisotopes / therapeutic use
  • New Zealand
  • Retrospective Studies
  • Thyroid Neoplasms*
  • Thyroidectomy / methods
  • Treatment Outcome

Substances

  • Iodine Radioisotopes