Somatic symptom profiles are associated with pre-treatment depression and anxiety symptom severity but not inpatient therapy outcomes

Psychother Res. 2023 Feb;33(2):211-221. doi: 10.1080/10503307.2022.2090870. Epub 2022 Jun 21.

Abstract

Objective: Although somatic symptoms are common among mental health patients, their association with symptom severity and inpatient treatment outcomes is not yet well understood.

Methods: Using a pre-post design and latent class analysis (LCA), 641 inpatients (63.4% female) were classified based on their self-reported somatic symptoms. We examined how the resulting somatic symptom classes related to depression and anxiety symptom severity pre-treatment (T1) and to symptom reduction post-treatment (T2).

Results: Our results suggest four somatic symptom classes, namely (1) unspecific/low somatic symptom burden, (2) sexual problems, (3) gastrointestinal symptoms with pain syndrome, and (4) cardiopulmonary symptoms. While class 1 indicated the lowest pre-treatment depression and anxiety symptom severity, class 2 reported high depressive symptoms coupled with low anxiety, class 3 reported moderate depressive and anxiety symptom severity, and class 4 reported the highest depressive and anxiety symptom burden. Somatic symptom classes, however, did not predict the degree of reduction in either depression or anxiety symptoms post-treatment.

Conclusions: These findings demonstrate somatic heterogeneity in mental health patients and reveal the relationship of somatic symptom patterns to affective symptom severity. Clinical implications are discussed.

Keywords: anxiety; clinical diagnosis; depression; latent class analysis; psychosomatic medicine; somatic symptoms.

MeSH terms

  • Anxiety / therapy
  • Anxiety Disorders / therapy
  • Depression / therapy
  • Female
  • Humans
  • Inpatients
  • Male
  • Medically Unexplained Symptoms*