We isolated a novel reassortant influenza A(H10N7) virus from a harbor seal in British Columbia, Canada, that died from bronchointerstitial pneumonia. The virus had unique genome constellations involving lineages from North America and Eurasia and polymerase basic 2 segment D701N mutation, associated with adaptation to mammals.
Keywords: British Columbia; Canada; H10N7; avian influenza; harbor seals; influenza; influenza A virus; reassortment; viruses; whole-genome sequencing.