Natural Reassortment of Eurasian Avian-Like Swine H1N1 and Avian H9N2 Influenza Viruses in Pigs, China

Emerg Infect Dis. 2022 Jul;28(7):1509-1512. doi: 10.3201/eid2807.220642.


Several zoonotic influenza A viruses detected in humans contain genes derived from avian H9N2 subtypes. We uncovered a Eurasian avian-like H1N1 swine influenza virus with polymerase basic 1 and matrix gene segments derived from the H9N2 subtype, suggesting that H9N2 viruses are infecting pigs and reassorting with swine influenza viruses in China.

Keywords: China; Eurasian avian-like swine H1N1 virus; avian H9N2 virus; influenza; pigs; viruses; zoonoses; zoonotic influenza A viruses.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Birds
  • China / epidemiology
  • Humans
  • Influenza A Virus, H1N1 Subtype* / genetics
  • Influenza A Virus, H9N2 Subtype* / genetics
  • Influenza, Human* / epidemiology
  • Orthomyxoviridae Infections* / veterinary
  • Phylogeny
  • Reassortant Viruses / genetics
  • Swine
  • Swine Diseases* / epidemiology