Pineal region teratoma with metastases in uncommon locations: a case report

J Med Case Rep. 2022 Jun 23;16(1):261. doi: 10.1186/s13256-022-03454-z.

Abstract

Background: We report a rare case in medical literature of a patient with pineal gland teratoma and uncommon metastases. Usually, metastases of this kind of tumor are located in several organs such as lung and breast, but here we found metastases to the spinal cord and vertebrae.

Case presentation: A 35-year-old Asian white man presented with diplopia and acute neural symptoms in the lower limbs such as numbness, tingling, and paralysis. His medical history was notable for pineal teratoma, treated 1 year previously with surgery, radiotherapy, and chemotherapy. Physical examination of the lower limbs showed absent reflexes and sensation with muscle power scale score of 1 in both limbs. Magnetic resonance imaging of brain and spine revealed many lesions in various locations, most compatible with neural, spinal, and vertebral metastases. Unfortunately, the patient died suddenly before any intervention was carried out.

Conclusion: It is extremely rare for pineal region teratoma to metastasize to the spinal cord and vertebrae, thus more vigilant observation and examination should be provided to patients with pineal teratoma to detect any new lesions and prevent them from becoming dangerous.

Keywords: CNS tumors; Case report; Metastasis; Pineal region; Teratoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Neoplasms* / diagnostic imaging
  • Brain Neoplasms* / pathology
  • Brain Neoplasms* / therapy
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Pinealoma* / diagnostic imaging
  • Pinealoma* / therapy
  • Teratoma* / diagnostic imaging
  • Teratoma* / pathology
  • Teratoma* / therapy

Supplementary concepts

  • Pineal Teratoma