Engineered exoASO-STAT6: a potent monotherapy for oral squamous cell carcinoma

Future Oncol. 2022 Aug;18(25):2767-2769. doi: 10.2217/fon-2022-0496. Epub 2022 Jun 29.

Authors

Vijayashree Priyadharsini Jayaseelan¹, Arumugam Paramasivam²

Affiliations

¹ Clinical Genetics Lab, Centre for Cellular & Molecular Research, Saveetha Dental College & Hospital, Saveetha Institute of Medical & Technical Sciences (SIMATS), Saveetha University, Chennai, India.
² Molecular Biology Lab, Centre for Cellular & Molecular Research, Saveetha Dental College & Hospital, Saveetha Institute of Medical & Technical Sciences (SIMATS), Saveetha University, Chennai, India.

PMID: 35766123
DOI: 10.2217/fon-2022-0496

No abstract available

Keywords: antisense oligonucleotide; carcinoma; exosomes; monotherapy; tumor-associated macrophages.

MeSH terms

Carcinoma, Squamous Cell* / drug therapy
Carcinoma, Squamous Cell* / pathology
Cell Line, Tumor
Exosomes*
Head and Neck Neoplasms*
Humans
Mouth Neoplasms* / drug therapy
Mouth Neoplasms* / pathology
STAT6 Transcription Factor
Squamous Cell Carcinoma of Head and Neck

Substances

STAT6 Transcription Factor
STAT6 protein, human