Investigation of movement-related behaviors and energy compensation in people living with liver disease: A scoping review

J Sports Sci. 2022 Jun;40(12):1299-1307. doi: 10.1080/02640414.2022.2065087. Epub 2022 Jun 29.


The importance of integrated movement behaviours (MB, i.e., physical activity [PA], sedentary behaviour, and sleep) and their interdependence for health has been recently discussed in the literature. The proposition that the amount of time spent in any one of these behaviours may impact the amount of time spent in another is supported by the ActivityStat hypothesis. The aim of this review is to (1) to assess whether individuals with liver disease display MB and/or energy (i.e., total energy expenditure [EE], basal EE, resting EE, and activity EE) compensation throughout the day and/or days; and (2) to examine whether a prescribed PA intervention triggers compensatory responses. Documents were included if they focused on people living with liver disease; analysed MB and/or EE components; were data-based; and were published in English. Fifteen documents were included in the final synthesis. The one finding that addressed research question 1 showed no compensatory response. As for research question 2, most of the findings suggest no compensation effects in response to a PA intervention. There is insufficient evidence to support the ActivityStat hypothesis in people living with liver disease. Further research should be conducted to test this hypothesis using standardized methodological procedures.

Keywords: ActivityStat; energy expenditure; exercise; patients; physical activity.

Publication types

  • Systematic Review

MeSH terms

  • Energy Metabolism* / physiology
  • Exercise / physiology
  • Humans
  • Liver Diseases*
  • Rest
  • Sedentary Behavior