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. 2022 Jul 21;387(3):275-277.
doi: 10.1056/NEJMc2202092. Epub 2022 Jun 29.

Duration of Shedding of Culturable Virus in SARS-CoV-2 Omicron (BA.1) Infection

Julie Boucau  1 , Caitlin Marino  1 , James Regan  2 , Rockib Uddin  3 , Manish C Choudhary  2 , James P Flynn  2 , Geoffrey Chen  3 , Ashley M Stuckwisch  3 , Josh Mathews  3 , May Y Liew  3 , Arshdeep Singh  3 , Taryn Lipiner  3 , Autumn Kittilson  2 , Meghan Melberg  2 , Yijia Li  2 , Rebecca F Gilbert  3 , Zahra Reynolds  3 , Surabhi L Iyer  3 , Grace C Chamberlin  3 , Tammy D Vyas  3 , Marcia B Goldberg  3 , Jatin M Vyas  3 , Jonathan Z Li  2 , Jacob E Lemieux  3 , Mark J Siedner  3 , Amy K Barczak  3
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Duration of Shedding of Culturable Virus in SARS-CoV-2 Omicron (BA.1) Infection

Julie Boucau et al. N Engl J Med. .
No abstract available

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Figures

Figure 1
Figure 1. Viral Decay and Time to Negative Viral Culture.
Panel A shows viral-load decay from the time of the first positive polymerase-chain-reaction (PCR) assay. Viral loads from nasal-swab samples obtained from individual participants are shown. Each circle or triangle represents a sample obtained on the specified day. The median viral load at each time point for each variant is also shown. LOD denotes limit of detection. Panels B through E show Kaplan–Meier survival curves for the time from an initial positive PCR assay to a negative PCR assay, according to viral variant (Panel B) and vaccination status (Panel D), and the time from an initial positive PCR assay to a negative viral culture, according to viral variant (Panel C) and vaccination status (Panel E). In all panels, shaded areas indicate 95% confidence intervals. Sequencing showed that all omicron variant strains were the subvariant BA.1, inclusive of sublineages.
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