1 Department of Emergency, Intensive Care Medicine and Anesthesia, Fondazione 'Policlinico Universitario A. Gemelli' IRCCS, L.go F. Vito, 00168, Rome, Italy. dlgrieco@outlook.it.
2 Department of Anesthesiology and Intensive Care Medicine, Catholic University of The Sacred Heart, L.go F. Vito, 00168, Rome, Italy. dlgrieco@outlook.it.
3 Laboratório de Pneumologia LIM-09, Disciplina de Pneumologia, Heart Institute (Incor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil.
4 Research and Education Institute, Hospital Sírio-Libanes, Sao Paulo, Brazil.
5 Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.
6 Department of Anesthesia and Intensive Care Medicine, Royal United Hospital Bath, Bath, UK.