Allergen specific immunoglobulin E (sIgE) test plays a key role in pathogenic diagnosis of allergic diseases. In recent years, several in vitro diagnostic methods and technology are available in clinical application, however, there exists discrepancies due to different diagnostic methodology and lacking interlaboratory commutability. Proper interpretation of sIgE reports needs combination with clinical history and (or) other diagnostic methods. There is no accessible clinical interpretation approach in clinical practices. Thus, the consensus summarizes the aspects of in vitro diagnostic techniques, allergen items and clinical implications, expert panel draft the clinical interpretation approach which aims to provide a reference for community physicians, allergists, laboratory physician and other health care givers, and finally avoid misdiagnosis and mistreatment of allergic diseases.
过敏原特异性IgE（specific IgE，sIgE）检测是过敏性疾病病因诊断的重要方法。当前临床应用的sIgE检测方法和检测体系多样，检测结果存在一定差异，缺乏实验室间互认的检测结果。正确解读sIgE检测结果需结合病史和（或）必要的其他诊断方法，但是国内尚无指导临床医师及检验医师正确解读结果的临床路径。为此，组织专家组制定本共识，全面阐述常用sIgE检测方法、检测项目及结果的临床意义，制订解读临床路径，旨在为基层医师、变态反应专科医师、检验医师等提供临床指导，避免误诊误治。.