Transcranial direct current stimulation (tDCS) modulates motor execution in a limb reaching task

Eur J Neurosci. 2022 Aug;56(4):4445-4454. doi: 10.1111/ejn.15756. Epub 2022 Jul 18.

Abstract

The majority of human activities show a trade-off between movement speed and accuracy. Here we tested 16 participants in a quick pointing action after 20 minutes (2 mA) of transcranial direct current stimulation (tDCS) delivered at the supplementary motor area in a single-blind crossover design study for testing the feedforward components in the control of action. tDCS stimuli were delivered in three randomized sessions of stimulations as anodal, cathodal and sham as a control. The task performed pre- and post-tDCS stimulation, was to point as fast and as precise as possible with the big toe to targets having different sizes (2 and 8 cm; Width) and positioned at different distances (20 and 60 cm; Distance). An optoelectronic motion capture system was used to collect the kinematics of movement. The result indicates that individuals after receiving anodal stimulation decreased their movement time and increased their movement speed, while the opposite happened after receiving a cathodal stimulation. The scarcity of studies in this area invites us to plan a research that aims at the trade-off especially in the clinical settings.

Keywords: brain stimulation; lower limb; motor control; supplementary motor area.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cross-Over Studies
  • Humans
  • Motor Cortex* / physiology
  • Movement
  • Single-Blind Method
  • Transcranial Direct Current Stimulation*

Associated data

  • figshare/10.6084/m9.figshare.20039762