Ten-year trends in hospitalizations related to cocaine abuse in France

Fundam Clin Pharmacol. 2022 Dec;36(6):1128-1132. doi: 10.1111/fcp.12815. Epub 2022 Jul 22.


In France, the abuse/misuse of psychoactive substances, including cocaine, is monitored via spontaneous notifications, and under-reporting is its main limitation. Therefore, the French national hospital discharge database (Programme de Médicalisation des Systèmes d'information [PMSI]) was used to identify all hospital stays possibly due to complications related to cocaine use. The objective was to determine the main trends in the rate of cocaine-related hospitalizations from 2010 to 2019 by age category and by areas. Relevant PMSI data were extracted using the International Classification of Diseases (10th edition). In France, hospitalizations for cocaine-related complications increased by fourfold (2461 in 2010, 9843 in 2019, +300%). This increase was similar in men and women and was observed in each age category. Patients were mainly men (75% in 2010 and in 2019), with a median age of 38.5 and 35.2 years for men and women, respectively, in 2019. Cocaine poisoning in pediatric patients (0-9 years) concerned less than 10 patients in 2010 and 21 patients in 2019. PMSI data analysis shows an overall increase of cocaine-related hospitalizations in France from 2010 to 2019 that can be linked in part to an increasing recreational use. The increase of pediatric cases of cocaine poisoning suggests a trivialization of cocaine consumption.

Keywords: addictovigilance; cocaine; hospitalization; national hospital database.

MeSH terms

  • Child
  • Cocaine* / adverse effects
  • Cocaine-Related Disorders* / epidemiology
  • Databases, Factual
  • Female
  • France / epidemiology
  • Hospitalization
  • Humans
  • International Classification of Diseases
  • Length of Stay
  • Male


  • Cocaine