Heart failure caused by Takayasu's arteritis in the time of COVID-19: a case report

ESC Heart Fail. 2022 Oct;9(5):3602-3607. doi: 10.1002/ehf2.14054. Epub 2022 Jul 9.


The case of a 35-year-old female with heart failure is presented, where the symptoms overlap with the heterogeneous manifestations of coronavirus disease 2019 (COVID-19). Those similarities and a recent shift in priorities during the SARS-CoV-2 pandemic delayed the recognition of acute heart failure in this patient. During the differential diagnostic process, obliterative disease was discovered in the bilateral subclavian and right renal arteries, and the latter resulted in uncontrolled hypertension, which played a significant role in the development of heart failure. The aetiology of vascular alterations turned out to be Takayasu's arteritis. Diagnosing Takayasu's arteritis is typically not straightforward due to its nonspecific signs and symptoms. Therefore, it can be concluded from our case report that the rising incidence of COVID-19 and focus on ruling out infection can potentially defer alternative, but appropriate diagnostic tests, particularly for certain conditions like rare diseases. Early identification and intervention is especially important for treating acute heart failure, whereas delay increases the risk of severe complications and mortality.

Keywords: Acute heart failure; COVID-19; Takayasu's arteritis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • COVID-19* / complications
  • Female
  • Heart Failure* / complications
  • Heart Failure* / etiology
  • Humans
  • Hypertension* / complications
  • SARS-CoV-2
  • Takayasu Arteritis* / complications
  • Takayasu Arteritis* / diagnosis