Water and aging

Clin Geriatr Med. 1987 May;3(2):403-11.


Having evolved from the sea and developed from an embryo, the species and the individual lose water--the medium and solvent wherein these processes occur--continually as they age. From an embryo, which is about 90% water, to a senescent individual in the tenth decade, there is a decline in body water to 60% or below. This loss in body water has profound effects on pathophysiology, making older persons susceptible to both under- and overhydration because they have a smaller volume of distribution for exogenous water. A colloid osmotic macromolecular aggregation model has been hypothesized to explain water loss in aging individuals.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Aging*
  • Anemia, Sickle Cell / metabolism
  • Animals
  • Blood Volume
  • Body Water / metabolism*
  • Cataract / metabolism
  • Child
  • Child, Preschool
  • Colloids
  • Erythrocyte Aging
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Middle Aged
  • Osmotic Pressure
  • Rats


  • Colloids