Insights from the molecular docking analysis of colistin with the PmrA protein model from Acinetobacter baumannii

Shalini Ganeshan; Mohammad Reza Shakibaie; Rajaguru Rajagopal

doi:10.6026/97320630018041

Insights from the molecular docking analysis of colistin with the PmrA protein model from Acinetobacter baumannii

Bioinformation. 2022 Jan 31;18(1):41-49. doi: 10.6026/97320630018041. eCollection 2022.

Authors

Shalini Ganeshan¹, Mohammad Reza Shakibaie^{2

3}, Rajaguru Rajagopal⁴

Affiliations

¹ Department of Biotechnology, Tips college of arts and science, Coimbatore, Tamil Nadu 641107, India.
² Department of Microbiology and Virology, Kerman University of Medical Sciences, Kerman, Iran.
³ Environmental Health Engineering Research Center, Kerman University of Medical Science, Kerman, Iran.
⁴ Research Scholar Department of Pharmaceutics, Mother Theresa Post Graduate and Research Institute of Health Sciences, Pondicherry-605006, India.

Abstract

Acinetobacter baumannii (AB) is one of the most common causes of nosocomial infections. Therefore, it is of interest to design and develop drugs against Acinetobacter baumannii. A strain of AB showing MIC 32 µg/ml against colistin was isolated from a hospital environment in Iran. Hence, we document data to glean insights from the molecular docking analysis of colistin with the PmrA protein from this bacterium.

Keywords: Acinetobacter baumannii; model quality; molecular docking; protein modeling.