Unusual complication of Herpes simplex encephalitis: complete Klüver-Bucy syndrome

BMJ Case Rep. 2022 Jul 11;15(7):e250745. doi: 10.1136/bcr-2022-250745.

Abstract

Klüver-Bucy syndrome is a rare neurobehavioral disorder caused by a bilateral temporal lobe lesion affecting the hippocampus and amygdala; clinically characterised by hyperorality, hypermetamorphosis, placidity, altered sexual behaviour, eating, disorders and visual impairment, agnosia and amnesia. However, the complete syndrome is rarely seen, and diagnosis does not require all the symptoms to be manifested simultaneously.We describe a patient who developed a complete Klüver-Bucy syndrome secondary to bilateral temporal involvement due to herpetic encephalitis.

Keywords: Epilepsy and seizures; Headache (including migraines); Infection (neurology); Memory Disorders; Neuroimaging.

Publication types

  • Case Reports

MeSH terms

  • Amnesia
  • Encephalitis, Herpes Simplex* / complications
  • Encephalitis, Herpes Simplex* / diagnosis
  • Hippocampus
  • Humans
  • Kluver-Bucy Syndrome* / etiology
  • Temporal Lobe / pathology