Aging of the Immune System: Research Challenges to Enhance the Health Span of Older Adults

doi:10.3389/fragi.2020.602108

Editorial

. 2020 Oct 15:1:602108.

doi: 10.3389/fragi.2020.602108. eCollection 2020.

Aging of the Immune System: Research Challenges to Enhance the Health Span of Older Adults

Laura Haynes¹

Affiliations

PMID: 35822168
PMCID: PMC9261332
DOI: 10.3389/fragi.2020.602108

Editorial

Aging of the Immune System: Research Challenges to Enhance the Health Span of Older Adults

Laura Haynes. Front Aging. 2020.

. 2020 Oct 15:1:602108.

doi: 10.3389/fragi.2020.602108. eCollection 2020.

Author

Laura Haynes¹

Affiliation

¹ UConn Center on Aging, University of Connecticut School of Medicine, Farmington, CT, United States.

PMID: 35822168
PMCID: PMC9261332
DOI: 10.3389/fragi.2020.602108

No abstract available

Keywords: aging immune system; cellular senescence; geroscience hypothesis; health span; inflammaging.

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References

1. Akbar A. N., Fletcher J. M. (2005). Memory T cell homeostasis and senescence during aging. Curr. Opin. Immunol. 17, 480–485. 10.1016/j.coi.2005.07.01910.1016/j.coi.2005.07.019 | Google Scholar - DOI - DOI - PubMed
1. Barzilai N., Crandall J. P., Kritchevsky S. B., Espeland M. A. (2016). Metformin as a tool to target aging. Cell Metab. 23, 1060–1065. 10.1016/j.cmet.2016.05.011 - DOI - PMC - PubMed
1. Blomberg B. B., Frasca D. (2013). Age effects on mouse and human B cells. Immunol. Res. 57, 354–360. 10.1007/s12026-013-8440-9 - DOI - PMC - PubMed
1. Braig M., Lee S., Loddenkemper C., Rudolph C., Peters M., Schlegelberger B., et al. (2005). Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 436, 660–665. 10.1038/nature03841 - DOI - PubMed
1. Bruunsgaard H. (2006). The clinical impact of systemic low-level inflammation in elderly populations. With special reference to cardiovascular disease, dementia and mortality. Dan. Med. Bull. 53, 285–309. - PubMed

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[1] Akbar A. N., Fletcher J. M. (2005). Memory T cell homeostasis and senescence during aging. Curr. Opin. Immunol. 17, 480–485. 10.1016/j.coi.2005.07.01910.1016/j.coi.2005.07.019 | Google Scholar - DOI - DOI - PubMed

[2] Akbar A. N., Fletcher J. M. (2005). Memory T cell homeostasis and senescence during aging. Curr. Opin. Immunol. 17, 480–485. 10.1016/j.coi.2005.07.01910.1016/j.coi.2005.07.019 | Google Scholar - DOI - DOI - PubMed

[3] Barzilai N., Crandall J. P., Kritchevsky S. B., Espeland M. A. (2016). Metformin as a tool to target aging. Cell Metab. 23, 1060–1065. 10.1016/j.cmet.2016.05.011 - DOI - PMC - PubMed

[4] Barzilai N., Crandall J. P., Kritchevsky S. B., Espeland M. A. (2016). Metformin as a tool to target aging. Cell Metab. 23, 1060–1065. 10.1016/j.cmet.2016.05.011 - DOI - PMC - PubMed

[5] Blomberg B. B., Frasca D. (2013). Age effects on mouse and human B cells. Immunol. Res. 57, 354–360. 10.1007/s12026-013-8440-9 - DOI - PMC - PubMed

[6] Blomberg B. B., Frasca D. (2013). Age effects on mouse and human B cells. Immunol. Res. 57, 354–360. 10.1007/s12026-013-8440-9 - DOI - PMC - PubMed

[7] Braig M., Lee S., Loddenkemper C., Rudolph C., Peters M., Schlegelberger B., et al. (2005). Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 436, 660–665. 10.1038/nature03841 - DOI - PubMed

[8] Braig M., Lee S., Loddenkemper C., Rudolph C., Peters M., Schlegelberger B., et al. (2005). Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 436, 660–665. 10.1038/nature03841 - DOI - PubMed

[9] Bruunsgaard H. (2006). The clinical impact of systemic low-level inflammation in elderly populations. With special reference to cardiovascular disease, dementia and mortality. Dan. Med. Bull. 53, 285–309. - PubMed

[10] Bruunsgaard H. (2006). The clinical impact of systemic low-level inflammation in elderly populations. With special reference to cardiovascular disease, dementia and mortality. Dan. Med. Bull. 53, 285–309. - PubMed

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Aging of the Immune System: Research Challenges to Enhance the Health Span of Older Adults

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Aging of the Immune System: Research Challenges to Enhance the Health Span of Older Adults

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