Evidence for a signal peptide at the amino-terminal end of human mitochondrial aldehyde dehydrogenase

FEBS Lett. 1987 May 11;215(2):233-6. doi: 10.1016/0014-5793(87)80152-7.

Abstract

A full-length cDNA clone coding for human mitochondrial aldehyde dehydrogenase (ALDH I) was isolated from a human fetal muscle cDNA library. Sequence analysis revealed structural similarities between the amino-terminal end of ALDH I and other known targeting sequences responsible for protein uptake into the mitochondria.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehyde Dehydrogenase / analysis*
  • Amino Acid Sequence
  • Cloning, Molecular
  • DNA / analysis
  • Humans
  • Mitochondria / enzymology*
  • Protein Sorting Signals / analysis*

Substances

  • Protein Sorting Signals
  • DNA
  • Aldehyde Dehydrogenase

Associated data

  • GENBANK/X05409