Breakthrough Hemolysis in PNH with Proximal or Terminal Complement Inhibition

N Engl J Med. 2022 Jul 14;387(2):160-166. doi: 10.1056/NEJMra2201664.

Authors

Rosario Notaro¹, Lucio Luzzatto¹

Affiliation

¹ From Istituto per lo Studio, la Prevenzione e la Rete Oncologica (R.N.), and the University of Florence (L.L.) - both in Florence, Italy; and the Department of Hematology and Blood Transfusion, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania (L.L.).

PMID: 35830642
DOI: 10.1056/NEJMra2201664

No abstract available

Publication types

Review

MeSH terms

Complement Inactivating Agents* / therapeutic use
Complement System Proteins / physiology
Hemoglobinuria, Paroxysmal* / complications
Hemoglobinuria, Paroxysmal* / drug therapy
Hemolysis* / drug effects
Hemolysis* / physiology
Humans

Substances

Complement Inactivating Agents
Complement System Proteins