Innate riddle of CD4+ T cells and the control of enteric infections

Ankit Malik; Bana Jabri

doi:10.1016/j.immuni.2022.06.017

Innate riddle of CD4⁺ T cells and the control of enteric infections

Immunity. 2022 Jul 12;55(7):1145-1147. doi: 10.1016/j.immuni.2022.06.017.

Authors

Ankit Malik¹, Bana Jabri²

Affiliations

¹ Department of Medicine, The University of Chicago, Chicago, IL, USA.
² Department of Medicine, The University of Chicago, Chicago, IL, USA. Electronic address: bjabri@bsd.uchicago.edu.

PMID: 35830821
DOI: 10.1016/j.immuni.2022.06.017

Abstract

Intra-epithelial T cells make up a significant proportion of immune cells in the body, yet their development and function remain an enigma. In this issue of Immunity, Parsa et al. (2022) describe the differentiation and cross-protective function of CD4⁺ intra-epithelial T cells against enteric viruses.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

MeSH terms

CD4-Positive T-Lymphocytes
Immunity, Innate*
Intestine, Small*
Lymphocyte Count

Grants and funding

P30 DK042086/DK/NIDDK NIH HHS/United States