Reflection About the Ancient Emergence of HTLV-2 Infection

Jorge Casseb; Luciano Rodrigo Lopes

doi:10.1089/AID.2022.0019

Reflection About the Ancient Emergence of HTLV-2 Infection

AIDS Res Hum Retroviruses. 2022 Dec;38(12):933-938. doi: 10.1089/AID.2022.0019. Epub 2022 Aug 29.

Authors

Jorge Casseb¹, Luciano Rodrigo Lopes²

Affiliations

¹ Laboratory of Dermatology and Immunodeficiencies, Department of Dermatology, University of São Paulo Medical School, Brazil/Institute of Tropical Medicine of São Paulo, São Paulo, Brazil.
² Bioinformatics and Biomedical Data Science Division, Health Informatics Department, Federal University of Sao Paulo-Unifesp, São Paulo, Brazil.

PMID: 35833459
DOI: 10.1089/AID.2022.0019

Abstract

During millions of years, viruses have emerged and reemerged, with imbalance of photogenicity and transmissivity overtime. This letter describes that sometimes the nomenclature is uncertain what may actually happen during retrovirus evolution nowadays. This article discusses a possibility that human T-lymphotropic virus type 2 (HTLV-2) has been processed to incorporate the human genome in the last millions of years. Persistent viruses such as human immunodeficiency virus type 1 (HIV-1), HIV-2, and human T cell lymphotropic type 2 may also have potential of endogenization instead of a cytolytic process in a long time.

Keywords: HTLV-1; HTLV-2; endogenization; retroviruses.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

HIV Infections*
HIV-1*
HTLV-II Infections* / epidemiology
Human T-lymphotropic virus 1* / genetics
Human T-lymphotropic virus 2
Humans