The Impact of Mindfulness-Based Stress Reduction (MBSR) on Psychological Outcomes and Quality of Life in Patients With Lung Cancer: A Meta-Analysis

Xu Tian; Li-Juan Yi; Chen-Si-Sheng Liang; Lei Gu; Chang Peng; Gui-Hua Chen; Maria F Jiménez-Herrera

doi:10.3389/fpsyg.2022.901247

The Impact of Mindfulness-Based Stress Reduction (MBSR) on Psychological Outcomes and Quality of Life in Patients With Lung Cancer: A Meta-Analysis

Front Psychol. 2022 Jun 28:13:901247. doi: 10.3389/fpsyg.2022.901247. eCollection 2022.

Authors

Xu Tian¹, Li-Juan Yi², Chen-Si-Sheng Liang³, Lei Gu⁴, Chang Peng⁵, Gui-Hua Chen⁶, Maria F Jiménez-Herrera¹

Affiliations

¹ Nursing Department, Universitat Rovira i Virgili, Tarragona, Spain.
² School of Nursing, Hunan Traditional Chinese Medical College, Zhuzhou, China.
³ Medical School, Hunan Traditional Chinese Medical College, Zhuzhou, China.
⁴ Sports and Arts College, Hunan Traditional Chinese Medical College, Zhuzhou, China.
⁵ College of Physical Education, Hunan Traditional Chinese Medical College, Zhuzhou, China.
⁶ Department of Nursing, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Abstract

Objective: The impact of the mindfulness-based stress reduction (MBSR) program on psychological outcomes and quality of life (QoL) in lung cancer patients remains unclear. This meta-analysis aimed to evaluate the effectiveness of the MBSR program on psychological states and QoL in lung cancer patients.

Methods: Eligible studies published before November 2021 were systematically searched from PubMed, EMBASE, Cochrane Library, PsycINFO, China National Knowledge Infrastructure (CNKI), and Wanfang databases. The risk of bias in eligible studies was assessed using the Cochrane tool. Psychological variables and QoL were evaluated as outcomes. We used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system to grade the levels of evidence. Statistical analysis was conducted using RevMan 5.4 and STATA 14.0.

Results: A total of 17 studies involving 1,680 patients were included for meta-analysis eventually. MBSR program significantly relieved cancer-related fatigue (standard mean difference [SMD], -1.26; 95% confidence interval [CI], -1.69 to -0.82; moderate evidence) and negative psychological states (SMD, -1.35; 95% CI, -1.69 to -1.02; low evidence), enhanced positive psychological states (SMD, 0.91; 95% CI, 0.56-1.27; moderate evidence), and improved quality of sleep (MD, -2.79; 95% CI, -3.03 to -2.56; high evidence). Evidence on MBSR programs' overall treatment effect for QoL revealed a trend toward statistical significance (p = 0.06, low evidence).

Conclusion: Based on our findings, the MBSR program shows positive effects on psychological states in lung cancer patients. This approach should be recommended as a part of the rehabilitation program for lung cancer patients.

Systematic review registration: https://archive.org/details/osf-registrations-mwvbq-v1, identifier: 10.17605/OSF.IO/MWVBQ.

Keywords: lung cancer; meta-analysis; mindfulness-based stress reduction; physical and psychological wellbeing; quality of life.

Publication types

Systematic Review