Acne treatment review and future perspectives

Dermatol Ther. 2022 Sep;35(9):e15719. doi: 10.1111/dth.15719. Epub 2022 Jul 26.


Acne affects approximately 9% of people worldwide and is the most common skin condition in the USA. There are abundant topical and oral treatment options available for patients with acne. First-line agents include topical retinoids, azelaic acid, benzoyl peroxide, and combinations of these agents. For recalcitrant or more severe acne, oral medications, including oral antibiotics, isotretinoin, or hormonal therapy, may be considered. This review will also discuss the many advances being made in the treatment of acne vulgaris, from the development of microencapsulated medications to targeted treatments.

Keywords: acne; acne pathogenesis; acne treatment; minocycline foam; photodynamic therapy.

Publication types

  • Review

MeSH terms

  • Acne Vulgaris* / diagnosis
  • Acne Vulgaris* / drug therapy
  • Anti-Bacterial Agents / therapeutic use
  • Benzoyl Peroxide / therapeutic use
  • Dermatologic Agents* / therapeutic use
  • Humans
  • Isotretinoin / therapeutic use


  • Anti-Bacterial Agents
  • Dermatologic Agents
  • Isotretinoin
  • Benzoyl Peroxide