Conditional relative survival among patients with chronic lymphocytic leukaemia: A population-based study in the Netherlands

EJHaem. 2021 Dec 20;3(1):180-183. doi: 10.1002/jha2.368. eCollection 2022 Feb.

Abstract

Studies on conditional relative survival (CRS) in chronic lymphocytic leukaemia (CLL) have hitherto been lacking in the literature. We predicted up-to-date estimates of 5-year RS at diagnosis and for each additional year survived (i.e., CRS) up to 15 years post-diagnosis among CLL patients diagnosed during 2007-2020. We showed that 5-year CRS continues to decline gradually with each additional year survived in a contemporary era with access to novel-based agents, irrespective of age. This finding indicates that CLL patients continue to experience substantial excess mortality compared to an age- and sex-matched group from the general population.

Keywords: cancer epidemiology; chronic lymphocytic leukaemia; conditional survival; population‐based registry; relative survival.