Unified gene expression signature of novel NPM1 exon 5 mutations in acute myeloid leukemia

Véronique Lisi; Ève Blanchard; Michael Vladovsky; Éric Audemard; Albert Feghaly; Sébastien Lemieux; Josée Hébert; Guy Sauvageau; Vincent-Philippe Lavallée

doi:10.1182/bloodadvances.2022007300

Unified gene expression signature of novel NPM1 exon 5 mutations in acute myeloid leukemia

Blood Adv. 2022 Sep 13;6(17):5160-5164. doi: 10.1182/bloodadvances.2022007300.

Authors

Véronique Lisi^{1

2}, Ève Blanchard^{1

2}, Michael Vladovsky^{1

2}, Éric Audemard¹, Albert Feghaly¹, Sébastien Lemieux^{1

3

4}, Josée Hébert^{1

5

6

7

4}, Guy Sauvageau^{1

5

6

7

4}, Vincent-Philippe Lavallée^{1

2

8

4

9}

Affiliations

¹ The Leucegene Project, Université de Montréal, Montréal, QC, Canada.
² Centre Hospitalier Universitaire Sainte-Justine Research Center, Montréal, QC, Canada.
³ Department of Computer Science and Operations Research, Université de Montréal, Montréal, QC, Canada.
⁴ Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada.
⁵ Institut Universitaire d'Hémato-oncologie et de Thérapie Cellulaire, Centre Intégré Universitaire de Santé et de Services Sociaux de l'Est de l'Île de Montréal, Montréal, QC, Canada.
⁶ Quebec Leukemia Cell Bank, Centre de Recherche de l'Hôpital Maisonneuve-Rosemont, Montréal, QC, Canada.
⁷ Department of Medicine, Université de Montréal, Montréal, QC, Canada.
⁸ Department of Pediatrics, Université de Montréal, Montréal, QC, Canada.
⁹ Hematology and Oncology Division, Centre Hospitalier Universitaire Sainte-Justine, Montréal, QC, Canada.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Exons
Humans
Leukemia, Myeloid, Acute* / genetics
Mutation
Nuclear Proteins / genetics
Transcriptome*

Substances

Nuclear Proteins