Uterine angiolipoleiomyoma. A case report and systematic literature review

Folia Med (Plovdiv). 2022 Apr 30;64(2):341-347. doi: 10.3897/folmed.64.e60937.

Abstract

Uterine angiolipoleiomyomas are rare, benign mixed mesenchymal lesions. A manifestation in the gynecological region is quite uncommon, with few cases described in the literature so far. We present an interesting case of a 59-year-old woman diagnosed with uterine angiolipoleiomyoma, and the results of the conducted systematic review of the literature. The patient presented with a pelvic mass masquerading as a leiomyoma on the ultrasound and postmenopausal vaginal bleeding. At laparotomy, a large uterus was noticed and the histopathology set the diagnosis of angiolipoleiomyoma. Immunohistochemistry revealed negativity for Melan-A and HMB-45 melanoma-specific antibodies and positivity for Van Gieson and orcein histochemical stains.

Keywords: angiolipoleiomyoma benign uterine tumours.

Publication types

  • Case Reports
  • Systematic Review

MeSH terms

  • Female
  • Humans
  • Immunohistochemistry
  • Leiomyoma* / diagnostic imaging
  • Leiomyoma* / surgery
  • Middle Aged
  • Ultrasonography
  • Uterine Neoplasms* / diagnostic imaging
  • Uterine Neoplasms* / surgery
  • Uterus / pathology