Crisis of the Asian gut: associations among diet, microbiota, and metabolic diseases

Phatthanaphong Therdtatha; Akari Shinoda; Jiro Nakayama

doi:10.12938/bmfh.2021-085

Crisis of the Asian gut: associations among diet, microbiota, and metabolic diseases

Biosci Microbiota Food Health. 2022;41(3):83-93. doi: 10.12938/bmfh.2021-085. Epub 2022 Feb 9.

Authors

Phatthanaphong Therdtatha^{1

2}, Akari Shinoda³, Jiro Nakayama⁴

Affiliations

¹ Department of Innovative Science and Technology for Bio-industry, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
² Present address: Faculty of Agro-Industry, School of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand.
³ Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
⁴ Division of Systems Bioengineering, Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.

Abstract

The increase of lifestyle-related diseases in Asia has recently become remarkably serious. This has been associated with a change in dietary habits that may alter the complex gut microbiota and its metabolic function in Asian people. Notably, the penetration of modern Western diets into Asia, which has been accompanied by an increase in fat content and decrease in plant-derived dietary fiber, is restructuring the Asian gut microbiome. In this review, we introduce the current status of obesity and diabetes in Asia and discuss the links of changes in dietary style with gut microbiota alterations which may predispose Asian people to metabolic diseases.

Keywords: Asian Microbiome Project; bile acid; diabetes; diet; enterotype; gut microbiota; obesity.

Publication types

Review