Sweet sensors support stressed cell survival

Nathaniel J Himmel; Richard Benton

doi:10.1371/journal.pbio.3001705

Sweet sensors support stressed cell survival

PLoS Biol. 2022 Jul 22;20(7):e3001705. doi: 10.1371/journal.pbio.3001705. eCollection 2022 Jul.

Authors

Nathaniel J Himmel¹, Richard Benton¹

Affiliation

¹ Center for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.

Abstract

Gustatory receptors (Grs) are well known for their functions in sensory neurons in detecting food and toxins. An intriguing new study in PLOS Biology provides evidence for a role for Grs in Drosophila epithelia in protecting stressed cells from proteotoxicity.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Cell Survival
Drosophila Proteins* / metabolism
Drosophila* / metabolism
Epithelial Cells / metabolism
Proteostasis
Receptors, Cell Surface / metabolism
Taste / physiology

Substances

Drosophila Proteins
Receptors, Cell Surface