Chromosomes: A nuclear neighborhood conducive to centromere formation

Curr Biol. 2022 Jul 25;32(14):R776-R778. doi: 10.1016/j.cub.2022.06.020.

Abstract

Centromere identity is specified by nucleosomes containing the histone variant CENP-A. A new study reveals that subnuclear location dictates the efficiency with which a new centromere forms.

Publication types

  • Comment

MeSH terms

  • Autoantigens
  • Centromere / metabolism
  • Centromere Protein A
  • Chromosomal Proteins, Non-Histone* / metabolism
  • Histones* / genetics
  • Nucleosomes

Substances

  • Autoantigens
  • Centromere Protein A
  • Chromosomal Proteins, Non-Histone
  • Histones
  • Nucleosomes