Plasma concentration following oral administration of di- and flucloxacillin in infants and children

Pharmacol Toxicol. 1987 Mar;60(3):233-4. doi: 10.1111/j.1600-0773.1987.tb01741.x.

Abstract

The bioavailability of commercial liquid preparations of di- and flucloxacillin was compared in infants and children. The plasma concentrations following a dose of 12.5 mg/kg were equal within the two age groups. Infants 0-1 months old, however, demonstrated a better absorption than older children.

MeSH terms

  • Age Factors
  • Child, Preschool
  • Cloxacillin / analogs & derivatives*
  • Dicloxacillin / blood*
  • Floxacillin / blood*
  • Humans
  • Infant
  • Infant, Newborn
  • Kinetics

Substances

  • Floxacillin
  • Dicloxacillin
  • Cloxacillin