Photoredox synthesis of 6- and 7-membered ring scaffolds via N-centered radicals

Chem Commun (Camb). 2022 Aug 16;58(66):9206-9209. doi: 10.1039/d2cc02780a.


N-Containing heterocycles are important scaffolds due to their ubiquitous presence in bioactive compounds. Their synthesis has been considered as an important research field. In this work we report the access to 6- and 7-membered rings via a photoinduced strategy. To our knowledge, this work represents the first exemple of photo-induced 7-endo-trig cyclization with N-centered radicals.

MeSH terms

  • Cyclization*