Reappraisal of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1/INI-1 deficient tumor: Report of two cases

J Cancer Res Ther. 2022 Apr-Jun;18(3):780-783. doi: 10.4103/jcrt.JCRT_577_20.

Abstract

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 is a tumor suppressor gene located at chromosome 22q11.2. In the past decade, a major stride has been taken for decoding the molecular genesis of various tumors which has resulted in the addition of newer tumors harboring loss of this gene.

Keywords: Malignant extrarenal rhabdoid tumor; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 deficient sinonasal carcinoma; subfamily B member 1/INI-1.

Publication types

  • Case Reports

MeSH terms

  • Actins / genetics
  • Chromatin* / genetics
  • Humans
  • Neoplasms* / genetics
  • SMARCB1 Protein / genetics

Substances

  • Actins
  • Chromatin
  • SMARCB1 Protein