Potassium binders for patients with heart failure? The real enlightenment of the DIAMOND trial

Abstract

Graphical Abstract

Estimation of Number-Needed-to-Treat with Patiromer for 3 years to Prevent One Cardiovascular Death or Hospitalization for Heart failure in Patients with Heart Failure and a Reduced Ejection Fraction. Estimates of number-needed-to-treat for the RALES and EMPHASIS-HF trials are derived from calculations published by Ferreira et al. Estimates for the DIAMOND trial are derived from results presented by Butler et al. Abbreviations: MRA = mineralocorticoid receptor antagonist. HFrEF = heart failure and a reduced ejection fraction.