[Oxyurid infestation of small laboratory animals and its control with ivermectin]

Tierarztl Prax. 1987;15(1):93-7.
[Article in German]

Abstract

Investigations on parasitic infestations in laboratory animal stocks under different keeping conditions were carried out by fecal sample examination. Only barrier-kept mice and rats proved to be free of infections. Under semi-open or conventionally keeping conditions mice were infected with Aspiculuris tetraptera and Syphacia obvelata (max. 94.7 + 69.7%), rats with A. tetraptera and S. muris (48.6 + 94.9%), and hamsters and mongolian jirds with S. obvelata (26.6 and 16%, respectively). Ivermectin, added to the drinking water for the elimination of murine oxyurids, over a 24-hour period, in a dosage of 1.0 (males) and 1.6 mg/kg body weight (females), proved to be highly effective against A. tetraptera; the treatment of S. obvelata-infections requires a dosage correction.

Publication types

  • English Abstract

MeSH terms

  • Administration, Oral
  • Animals
  • Animals, Laboratory*
  • Cricetinae
  • Feces / parasitology
  • Female
  • Gerbillinae
  • Ivermectin / administration & dosage
  • Ivermectin / therapeutic use*
  • Male
  • Mice
  • Oxyuriasis / drug therapy
  • Oxyuriasis / veterinary*
  • Oxyuroidea / drug effects
  • Oxyuroidea / isolation & purification
  • Rats
  • Rodent Diseases / drug therapy*

Substances

  • Ivermectin